Royal National Hospital for Rheumatic Diseases Royal National Hospital for Rheumatic Diseases

نویسنده

  • Brian Stables
چکیده

Mycophenolate mofetil (MMF) is a pro-drug of the active metabolite of mycophenolic acid. It is a suppressor of T and B cell proliferation and adhesion and inhibits inosine monophosphate dehydrogenase that eventually blocks the progression to DNA synthesis and proliferation [1]. It does not inhibit the production of interleukins as does ciclosporin and tacrolimus. MMF has routinely been used in organ transplantation for many years and this remains the licensed indication for its use.

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تاریخ انتشار 2015